c 24 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T13368	YLF-466D	C24	AMPK
	YLF-466D (C24) is a newly developed AMPK activator, which inhibits platelet aggregation.		AMPK
T38291	C24 Phytosphingosine (t18:0/24:0)
	C24 Phytosphingosine (t18:0/24:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C24 Phytosphingosine (t...
T35810	C24 dihydro Ceramide (d18:0/24:0)	Cer(d18:0/24:0)
	C24 dihydro Ceramide is a sphingolipid that has been found in the stratum corneum of human skin.[1] It is found in higher concentrations in female sebum compared to male sebum.[2] C24 dihydro Ceramide levels positively c...
T38284	C24 dihydro 1-Deoxyceramide (m18:0/24:0)	C24 dihydro 1-Deoxyceramide (m18:0/24:0)
	C24 dihydro 1-Deoxyceramide (m18:0/24:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alan...
T38283	Tetracosanoyl-sulfatide	C24 3'-sulfo Galactosylceramide (d18:1/24:0)
	Tetracosanoyl-sulfatide is an endogenous sulfated glycolipid, which are also known as sulfatides . Tetracosanoyl-sulfatide is the major sulfatide in mature myelin in the central and peripheral nervous systems. Levels of ...
T38285	C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))	C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))	Others
	C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) is the predominant sulfate analog in the mature myelin sheath. C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) interacted with C-type lectin and immunoglobulin-like...		Others
T1845	B-Raf IN 1		Raf
	B-Raf IN 1 is a B-Raf (IC50: 24 nM) and c-Raf (IC50: 25 nM) inhibitor.		Raf
T10775	c-Fms-IN-2		c-Fms
	c-Fms-IN-2 is an inhibitor of c-FMS kinase (IC50 = 24 nM).		c-Fms
T21448	Abafungin	Bay w 6341,UNII-11DI31LWXF	Others
	Abafungin (Bay w 6341) is an antifungal agent with a broad-spectrum.		Others
T14363	AZ-23	AZ 23,AZ23	Trk receptor
	AZ-23 is an inhibitor of ATP-competitive and Trk kinase A/B/C. For TrkA, TrkB, FGFR1, Flt3, Ret, MuSk, Lck, the IC50s values are 2 nM, 8 nM, 24 nM, 52 nM, 55 nM, 84 nM, 99 nM, respectively.		Trk receptor
T11125	Durlobactam sodium salt	ETX2514 sodium salt	Antibacterial
	Durlobactam sodium salt (ETX2514 sodium salt) is an inhibitor of β-lactamase with IC50 values of 4 nM, 14 nM, and 190 nM for Class A KPC-2, Class C AmpC, and Class D OXA-24, respectively. Durlobactam sodium salt can be u...		Antibacterial
T5234	Glycoursodeoxycholic acid	Ursodeoxycholylglycine,GUDCA	Others , Endogenous Metabolite
	Glycoursodeoxycholic acid (Ursodeoxycholylglycine) is an acyl glycine and a bile acid-glycine conjugate. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of the colonic enviro...		Others , Endogenous Metabolite
T1415	Gemfibrozil	CI-719,Jezil,Decrelip,Lopid	P450 , Adrenergic Receptor , PPAR
	Gemfibrozil (CI-719) interacts with peroxisome proliferator-activated receptors (PPARalpha) resulting in PPARalpha-mediated stimulation of fatty acid oxidation and an increase in lipoprotein lipase (LPL) synthesis. Gemfi...		P450 , Adrenergic Receptor , PPAR
T1661	Crizotinib	PF-02341066	c-Met/HGFR , ROS , ALK , Autophagy , ROS Kinase
	Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.		c-Met/HGFR , ROS , ALK , Autophagy , ROS Kinase
T3641	NVP-BAW2881	BAW2881	Raf , VEGFR , Bcr-Abl
	NVP-BAW2881 (BAW2881) is a potent and selective VEGFR inhibitor (vascular endothelial growth factor receptor tyrosine kinase inhibitor) with activity to inhibit chronic and acute skin inflammation.		Raf , VEGFR , Bcr-Abl
T10167	5-Dehydroepisterol		Others
	5-Dehydroepisterol is an episterol derivative with anti-fungal activities. It can be formed by C-5 sterol desaturase and converted into 24-methylenecholesterol by 7-dehydrocholesterol reductase.		Others
T35979	Benastatin C
	Benastatin C is a polyketide synthase-derived benastatin that has been found inStreptomycesand has diverse biological activities.1,2It inhibits glutathione S-transferase (GST; IC50= 24 μg/ml for the rat liver enzyme).2Be...
T79354	CDK9-IN-24		CDK
	CDK9-IN-24 (compound 21a) is a potent and selective inhibitor of CDK9 that exhibits a pronounced inhibitory impact on tumor proliferation. It impedes cell growth and triggers apoptosis via the downregulation of Mcl-1 and...		CDK
T36961	Malformin C
	Malformin C is a natural fungus-derived bicyclic pentapeptide that has antibacterial properties, particularly against species of Bacillus. Malformin C potently blocks the ability of bleomycin to induce G2 arrest in human...
T36251	DP-C-4
	DP-C-4 is a Cereblon-based dual PROTAC for simultaneous degradation of EGFR and PARP[1]. DP-C-4 (1-50 μM; 24 hours) has degradation effects on EGFR and PARP simultaneously in a dose-dependent manner in SW1990 cells[1]. [...